Wealthy businessman Isaacman has been confirmed as the new administrator of NASA, capping an extraordinary confirmation journey where President Donald Trump put his name forward, withdrew it, and then renominated him.
Isaacman, an aviation enthusiast who became the first non-professional astronaut to perform a spacewalk, is also the first agency head in a generation to come directly from outside public service.
For numerous observers, the ultimate measure of his leadership will be judged on one pivotal challenge: whether it can send astronauts to the Moon ahead of the Chinese space program.
Trump has emphasized a goal for the United States to create a lasting moon outpost, both to enable harvesting materials and to act as a stepping stone for journeys to the Red Planet.
On Wednesday, the Senate confirmed the nomination with a bipartisan vote.
The President initially pulled the nomination in May, citing a "thorough review of past connections".
At the point, the president was engaged in a dispute with Elon Musk, one of his major contributors, with whom the nominee has business connections.
Isaacman has stated he is now fully behind the administration's goal to harvest the moon, placing him in disagreement with Elon Musk, who has said that focus on the moon is a detour from the goal of travelling to Mars.
In the present cosmic competition, nations are vying to exploit the lunar surface.
āNow is not the time for hesitation but a time for progress because if we lag, if we make a mistake, we may be permanently behind, and the consequences could change the balance of power here on Earth,ā he told lawmakers during his hearing.
The billionaire entrepreneur sees fostering more commercial rivalry as essential for meeting those targets, according to a recently leaked document laying out his vision for the agency.
In his Senate hearing, he stood by the strategy, which he developed when he was initially selected, but clarified it was a developing document.
His welcoming of rivalry could also lead to tension with Musk. Last week, he commended the granting of a major contract to Jeff Bezos's company, which is one of the primary competitors of SpaceX.
In the strategy paper, he proposed the agency should expand collaboration with the scientific community, envisioning the agency as a "catalyst for scientific discovery".
He highlighted the upcoming deployment of the Roman Space Telescope as a cornerstone project.
"Should we be approaching something groundbreaking - like launching Roman - I will explore every option to see it launched, even funding it myself if that's what it requires to produce the discoveries," he remarked.
According to reports, his fortune is estimated at around 1.2 billion dollars, made mostly from his financial services firm and the sale of his business that provided flight training and operated a private fleet of military aircraft.
The NASA administrator role will be his initial foray in public office, a break from the immediate predecessors who served as NASA chief.
He will replace Sean Duffy, who has acted as temporary leader since July.
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